State Medicaid Formularies: What You Need to Know About Covered Drugs

When you're on state Medicaid formularies, lists of drugs approved for coverage under each state's Medicaid program. Also known as Medicaid drug lists, these formularies determine what medications you can get at a low or no cost — and which ones require extra steps or aren't covered at all. Every state runs its own Medicaid program, so your formulary in Texas isn't the same as in New York. These lists aren't random — they're built by pharmacy and therapeutics committees using cost, safety, and clinical evidence to pick the most effective drugs at the lowest price.

Medicaid formularies often push for generic drugs, lower-cost versions of brand-name medications that work the same way because they save money without sacrificing results. That’s why pharmacists are legally required to substitute generics unless the doctor says no — a rule backed by the FDA Orange Book, the official directory that lists approved generic equivalents. But not all drugs are treated equally. Some require prior authorization, step therapy, or quantity limits. For example, a drug like Emsam or a high-cost biologic might need your doctor to prove you tried cheaper options first. This isn’t about denying care — it’s about controlling spending while keeping patients safe.

What you won’t find on a formulary? Drugs with serious safety risks, like opioids mixed with MAOIs, or those tied to dangerous interactions like NSAIDs with blood thinners. These are often excluded because the risk outweighs the benefit, especially for vulnerable populations. Even common meds like acetaminophen or aluminum hydroxide can be flagged if they carry hidden dangers — especially with long-term use or in patients with liver or kidney issues. The REMS programs, FDA safety systems for high-risk drugs also influence what gets on or off a formulary. If a drug needs special training or monitoring to use safely, Medicaid may limit access until those controls are in place.

And it’s not just about what’s covered — it’s about how you get it. Some states require you to use specific pharmacies or mail-order services. Others restrict coverage based on diagnosis or prior treatment history. If your medicine isn’t on the list, you can appeal. Many patients don’t know this — but formularies aren’t final. Doctors can request exceptions, and sometimes, a simple letter from your provider gets your drug approved.

What you’ll find below are real, practical guides that connect directly to how Medicaid formularies affect your care. From how pharmacists handle generic substitution under federal law, to why certain drugs like levothyroxine or alendronate are prioritized, to how drug-induced liver injury or steroid tapers are monitored under tight coverage rules — these posts show you the real-world impact of formulary decisions. You’ll learn how to navigate restrictions, understand why your prescription was denied, and what alternatives might actually work better — and cost less.