Sildenafil Citrate (Liquid V) is a PDE-5 inhibitor. PDE5 is an enzyme that breaks cGMP down in the body. By using Liquid V to inhibit this enzyme it has shown mainly to increase blood flow to the genitals of test subjects and has also shown a positive effect on subjects with pulmonary hypertension. Liquid V does this by relaxing the arterial walls leading to decreased pulmonary arterial resistance and pressure, reducing the workload of the heart. Liquid V is mostly known for its effect at increasing blood flow to genitals and has shown in research to be a very effective tool in treating males with sexual dysfunction even from side effects from other medications such as antidepressants. It has also shown extremely effective at treating general male erectile dysfunction (ED) in test subjects. Liquid V has also been shown to be a possible treatment of depression, anxiety disorders, schizophrenia and autism. These effects are mostly due to a heightened oxytocin release from the posterior pituitary. Researchers love Liquid V due to its strong erections and fast acting qualities, along with a shorter duration when compared to other PDE inhibitors. This gives researchers more control with Liquid V’s dosage, effect and wanted duration. We are proud to offer you only the highest quality Sildenafil Citrate for all your research needs. Ref: 1) Sildenafil Improves Microvascular O2 Delivery-to-Utilization Matching and Accelerates Exercise O2 Uptake Kinetics in Chronic Heart Failure.Sperandio PA, Oliveira MF, Rodrigues MK, Berton DC, Treptow E, Nery LE, Almeida DR, Neder JA. http://www.ncbi.nlm.nih.gov/pubmed/23023868 2) Cumulative response curves to enhance interpretation of treatment differences on the Self-Esteem And Relationship questionnaire for men with erectile dysfunction.Cappelleri JC, Zou KH, Bushmakin AG, Carlsson MO, Symonds T. http://www.ncbi.nlm.nih.gov/pubmed/23017067 3) Oxytocin: a therapeutic target for mental disorders.Matsuzaki M, Matsushita H, Tomizawa K, Matsui H. http://www.ncbi.nlm.nih.gov/pubmed/23007624 4) Right Ventricular Function Predicts Clinical Response to Specific Vasodilator Therapy in Patients with Pulmonary Hypertension.Giusca S, Jurcut R, Coman IM, Ghiorghiu I, Catrina D, Popescu BA, Dima L, Ginghina C. http://www.ncbi.nlm.nih.gov/pubmed/22985202 5) Influence of sildenafil on the antidepressant activity of bupropion and venlafaxine in the forced swim test in mice.Socala K, Nieoczym D, Wyska E, Poleszak E, Wlaz P. http://www.ncbi.nlm.nih.gov/pubmed/22940586 6) Sildenafil: 10-year application in clinical andrology in China].Shang XJ, Huang YF. http://www.ncbi.nlm.nih.gov/pubmed/22934523