Description
Details
TB 500 is a peptide that occurs naturally. It can be found in blood, and many tissues throughout the body, and is most notably present at the site of an injury. TB 500 plays a major role in healing, protecting and regenerating damaged tissues. The mechanism by which this takes place is believed to be two fold. One is it regulates Actin. Actin is an essential network of filaments found in all cells and is important in the process of migration, adhesion and cell proliferation. All these processes are crucial to healing and wound repair. Two is it activates progenitor cells. Progenitor cells are like stem cells but have some unique properties. They have the ability to differentiate into different cell types. They also produce cell signaling protein molecules and growth factors that accelerate healing. TB 500 is a very exciting compound that is growing rapidly in popularity. Its ability to assist in healing injuries is a valuable tool that will surely prove useful in our research. Refs: * Cytotherapy. 2008;10(6):543-50.Multipotent adult progenitor cells: their role in wound healing and the treatment of dermal wounds. Herdrich BJ, Lind RC, Liechty KW. Source University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. * Endothelial progenitor cell biology in disease and tissue regeneration Andrea L George, Pradeep Bangalore-Prakash, Shilpi Rajoria, Robert Suriano, Arulkumaran Shanmugam, Abraham Mittelman and Raj K Tiwari* Department of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA * Molecular Cardiology Thymosin β4 Is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell–Mediated Cardioprotection Rabea Hinkel, DVM; Chiraz El-Aouni, PhD; Tonia Olson, DVM; Jan Horstkotte, MD; Stefan Mayer; Sebastian Müller;; Michael Willhauck, MD; Christine Spitzweg, MD; Franz-Josef Gildehaus, PhD; Wolfgang Münzing, PhD; Ewald Hannappel, PhD; Ildiko Bock-Marquette, PhD; J. Michael DiMaio, MD; Antonis K. Hatzopoulos, PhD; Peter Boekstegers, MD*; Christian Kupatt, MD*