Cefadroxil Uses: What It Treats, How It Works, and What to Know

When you need an antibiotic for a bacterial infection, cefadroxil, a first-generation oral cephalosporin antibiotic used to treat common bacterial infections. Also known as Cefadroxil monohydrate, it’s often prescribed when penicillin isn’t an option or when a broader coverage is needed. Unlike some antibiotics that only work on a narrow range of bugs, cefadroxil covers several types of bacteria that cause skin, throat, and urinary tract infections. It’s not for viruses — no colds, flu, or most sore throats — but it’s very effective against strep, staph, and some urinary tract bugs.

Doctors often choose cefadroxil because it’s taken just once or twice a day, making it easier to stick with than pills that need to be spaced every 6 hours. It’s also commonly used in kids — think ear infections, impetigo, or strep throat — because it comes in a liquid form that tastes better than many alternatives. Compared to amoxicillin, a widely used penicillin-class antibiotic for respiratory and ear infections, cefadroxil has a slightly wider range against certain resistant strains, but it’s not stronger overall. It’s more about matching the right drug to the infection and patient history. If someone’s allergic to penicillin, cefadroxil might be a go-to — though cross-reactivity is possible, so doctors check carefully.

It’s not magic. You still need to finish the full course, even if you feel better after two days. Skipping doses or stopping early can let the toughest bacteria survive and come back stronger. Side effects? Most people tolerate it fine, but stomach upset, diarrhea, or mild rash can happen. Serious reactions like allergic swelling or severe diarrhea (C. diff) are rare but real. Always tell your doctor about other meds you’re taking — especially probenecid or blood thinners — because cefadroxil can interact.

It’s also not the first choice for every infection. For pneumonia or deep skin infections, stronger or IV antibiotics might be needed. But for common, mild-to-moderate cases — like a stubborn skin boil or a UTI that won’t clear — cefadroxil is a solid, affordable, and well-studied option. It’s been around for decades, and while newer drugs exist, it still holds its ground in outpatient care.

Below, you’ll find real-world guides on how cefadroxil fits into treatment plans, what to watch for, how it stacks up against other antibiotics like roxithromycin, a macrolide antibiotic used for respiratory infections, and when it’s the right pick over alternatives. Whether you’re a patient, a caregiver, or just trying to understand your prescription, these posts cut through the noise and give you clear, practical answers.